Associations between constipation symptoms and the sleep quality in non-dialysis chronic kidney disease patients: a cross-sectional study

INTRODUCTION Sleep disturbances, similarly to constipation‑related symptoms, are common problems in patients with chronic kidney disease (CKD) and associated worse health-related quality of life. OBJECTIVES The aim the study was investigate sleep conservatively treated CKD assess association between constipation that population. PATIENTS AND METHODS In this cross‑sectional study, 100 outpatients filled questionnaires addressing (The Medical Outcomes Study 12‑item Scale-Revised [MOS‑Sleep‑R]) symptoms (PAC‑SYM, Rome III criteria). RESULTS T scores none assessed domains differed across estimated glomerular filtration rate terciles (all P >0.05). from PAC-SYM abdominal stool subscales correlated all domains. both univariable multivariable regression models adjusted for key clinical data, functional constipation, less than 7 bowel movements a week, discomfort, pain as well too small were independently increased prevalence ratio decreased quality. CONCLUSIONS nondialysis CKD, disorders might have etiological factors constipation-related symptoms.